Nithya Chaithanya Yathi was born as the first son of Pandalam Raghava Panicker, a poet and professional teacher in Kerala. After his matriculation, he left home as a wandering mendicant to familiarize himself with the land and people of his country of birth. In those days, India was undivided. His wanderings took him to every nook and cranny of the subcontinent, both cities, and villages, of almost all parts of what is now India, Pakistan, and Bangladesh. He met all the great people of the subcontinent including great leaders like Mohandas Gandhi and poets of high repute. He sat at the feet of several spiritual masters, including Sufi fakirs, Jain munis and Buddhist monks, and Hindu teachers such as Ramana Maharshi and Nityananda.

After specializing in Philosophy and Psychology he taught these subjects in two Indian Universities. After serving as a faculty at the Sree Narayana College, Kollam moved to Mumbai to research on the physically challenged until his move to Chennai to teach at Ramakrishna Mission Vivekananda College in 1956. He again sat at the feet of highly reputed sannyasis to learn Vedanta, Samkhya, Yoga, Mimamsa, Indian poetics, and literature.

In 1951, he accepted Nataraja Guru as his spiritual preceptor and after Nataraja Guru left his body, Guru Nitya functioned as the continuator of Narayana Guru and Nataraja Guru as Guru and Head of Narayana Gurukula. As Narayana Gurukula is a world community, the Guru has to act as a liaison between all members of the Gurukula at an interpersonal level in the teacher-taught context and as the enunciator of programs from time to time to spur the Gurukula community to work in unison, to help everyone to understand his or her integral value vision (svadharma).
Guru Nitya published over 120 books in Malayalam and 80 books in English, as well as countless articles on philosophy, psychology, social ethics, and aesthetics. He also functioned as the chairperson of the East-West University, as the Commissioner for World Education, and as a committed sponsor of the World Government of World Citizens.