Biochemistry Department

OUR DEPARTMENTS

Biochemistry – Publications

 Peer reviewed Journals
1Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy. Haritha NH, Nawab A, Vijayakurup V, Anto NP, Liju VB, Alex VV, Amrutha AN, Aiswarya SU, Swetha M, Vinod BS, Sundaram S, Guijarro MV, Herlevich T, Krishna A, Nestory NK, Bava SV, Sadasivan C, Zajac-Kaye M and Anto RJ. Frontiers in Oncology 2021 April; 11:656804. doi: 10.3389/fonc.2021.656804, IF-6.244. ISSN: 2234943X
2Chitosan Encapsulation Enhances the Bioavailability and Tissue Retention of Curcumin and Improves its Efficacy in Preventing B[a]P-induced Lung Carcinogenesis. Vinod Vijayakurup, Arun Kumar T Thulasidasan, Mohan Shankar G, Archana.P Retnakumari, C Devika Nandan, Jannet Somaraj, Jayesh Antony, Vijai V Alex, Vinod Balachandran, Vijayasteltar Liju, Sankar Sundaram, Vinod Kumar G S, and Ruby Anto. Cancer Prevention Research 2019 Apr;12(4):225-236, IF- 4.021, ISSN: 1940-6207.
3Heteronemin, a marine natural product, sensitizes acute myeloid leukemia cells towards cytarabine chemotherapy by regulating farnesylation of Ras. Minakshi Saikia, Archana P Retnakumari, Shabna Anwar, Nikhil P Anto, Rashmi Mittal, Shabna Shah, Kavya S Pillai, Balachandran S Vinod, Vidya Peter, Reeba Thomas and Ruby John Anto. Oncotarget. 2018; 9:18115-18127. IF- 5.168, ISSN: 1949-2553
4Sensitized Luminescence from novel pyrazolone based β-diketonate complexes of Eu3+, D. B. Ambili Raj, S. V. Manoj, and B. S. Vinod, Bulletin of Pure & Applied Sciences- Section C, 2018,37: 64-69, ISSN 2320 320X
5Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2-Akt axis. Balachandran S Vinod, H H Nair, V Vijayakurup, A Shabna, S Shah, A Krishna, K S Pillai, S Thankachan & R J Anto. Cell Death Discovery 1, (2015) IF- 5.241 doi:10.1038/cddiscovery.2015.61, ISSN 2058-7716
6Phytochemicals as Chemosensitizers: From Molecular Mechanism to Clinical Significance. Balachandran S Vinod, T T Maliekal and R J Anto. Antioxid Redox Signal. 2013 Apr 10; 18(11):1307-48. doi: 10.1089/ars.2012.4573. IF- 7.407
7Mechanistic evaluation of the signaling events regulating curcumin-mediatedchemosensitization of breast cancer cells to 5-fluorouracil. Balachandran S Vinod, Jayesh Antony, Haritha H.Nair, Vineshkumar T Puliyappadamba, Minakshi Saikia, Sai Shyam Narayanan, Arathy Bevin and Ruby John Anto. Cell Death Dis. 2013 Feb 21; 4: e505. doi: 10.1038/cddis.2013.26.ISSN-2041-4889 IF- 5.99
8Curcumin sensitizes breast cancer cells to 5-FU through thymidylate synthase- dependent downregulation of NF-?B. Haritha H Nair, Balachandran S Vinod, Jayesh Antony, Minakshi Saikia, Ruby John Anto, Journal of Carcinogenesis 01/2012; Vol.11(Supplement 1): pp-S31
9Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its downregulation by curcumin is independent. Vineshkumar T P, Vino T Cheriyan, Smitha V Bava, Arun Kumar T Thulasidas, Balachandran S Vinod, Priya R Prabhu, Ranji Varghese, Arathy Bevin, Shalini Venugopal and Ruby John Anto. Mol Cancer. 2010 Aug 20; 9:220. doi: 10.1186/1476-4598-9-220.IF- 3.779
10ATF2 maintains a subset of neural progenitors through CBF1/Notch independent Hes-1 expression and synergistically activates the expression of Hes-1 in Notch dependent neural progenitors. Rajendran Sanalkumar, Chandrasekharan Lalitha Indulekha, Thulasi Sheela Divya, Mundackal Sivaraman Divya, Ruby John Anto, Balachandran S Vinod, SasidharanVidyanand, Balusamy Jagatha, Shalini Venugopal, Jackson James, J Neurochem. 2010 May; 113(4):807-18. IF-4.337
11Studies on the anti-hyperlipidemic Properties of Averrhoa bilimbi fruit in rats. Ambili S, A and Nagarajan. N.S. Planta Med. 2009; 75: 55-58.
12Hypolipidemic, antioxidant and cytotoxic properties of Benincasa hispida fruit juice. Ambili S, Anilkumar S and Subramoniam A. Biomedicine 2007;27(2):72-76.
13Human Epidermal Growth Factor Receptor signaling as a therapeutic target in breast cancer. Balachandran S Vinod and Ruby John Anto, Amala Research Bulletin 2006, 26, 18-27.
14Prevention and treatment of hyperlipidemia with neutraceuticals and herbal drugs in: Medicinal plants: Ethno-botanical Approach. Ambili S and Subramoniam. A. Agrobios (India), Jodpur (2006) pg.(319-345). ISBN: 81-7754-253-2
 
Conference proceedings
 
1Regulatory role of curcumin in overcoming chemoresistance to 5-FU in breast cancer cells via Cyclin D1 and Bcl2 ,Vinod B.S, Haritha H Nair and Ruby John Anto (2020) Proceedings on the International Seminar on Current status and Challenges for Conservation and Sustainable use of Biodiversity. Department of Zoology, Sree Narayana College, Kollam, Kerala (ISBN NO: 978-93-5396-871-7).
2Involvement of Mitogen activated protein kinases in the activation of AP-1 in 5-FU treated breast cancer cells. BS Vinod, DB Ambiliraj, SV.Manoj & Ruby J Anto (2018), Proceedings of the National Seminar on New Horizons in Cancer Treatment and Prevention: From Bench to Bedside (Pg. No:68-71) organized by Department of Chemistry & Biochemistry, SN College, Kollam, sponsored by DST (SERB) & KSCSTE held from 16th to 17th March 2018 held at SN College, Kollam, ISBN 978-93-5300-765-2
3Evaluation of the Chemosensitizing efficacy of Curcumin in 5-Fu chemotherapy against breast cancer. Swetha. M, Haritha H Nair, Liju V B, Aiswarya U.S, B.S Vinod and Ruby John Anto, Proceedings of the National Seminar on New Horizons in Cancer Treatment and Prevention: From Bench to Bedside organized by Department of Chemistry & Biochemistry, SN College, Kollam, sponsored by DST (SERB) & KSCSTE held from 16th to 17th March 2018 held at SN College, Kollam, ISBN 978-93-5300-765-2
4Chemosensitization as a strategy to overcome chemoresistance and side effects of Docetaxel; an Invitro study. BS Vinod, Haritha H Nair, V Vinod, A Shabna, S Shabna & Ruby J Anto (2017) National seminar on recent trends in advanced chemistry research (RTACR-2017) organized by Dept. Of Chemistry on 25th and 26th may 2017 sponsored by DST (SERB) & KSCSTE at Sree Narayana College, Kollam. ISBN 978-93-5268-873-9
5HER-2-Akt signaling axis regulates the efficacy of resveratrol in chemosensitizing HER-2-over-expressing breast cancer cells to docetaxel. Haritha H Nair, BS Vinod, V Vinod, Aiswarya U.S, Vijai V.Alex, Nesteena K.N, Ruby John Anto, at International Conference on Nutraceuticals and Chronic Diseases sponsored by Society for Nutraceuticals and Chronic diseases & IIT, Guwahati, Assam on September 1st – 3rd 2017

Biochemistry Department