History of the Department
Biochemistry as a complementary subject started at Sree Narayana College, Kollam in the academic year 1976-77. In the initial years the department offered complementary course for Botany, Zoology under graduate students. As of now Sree Narayana College is among one of the two colleges in University of Kerala, where students have the option to take Biochemistry/Chemistry as complementary for Botany and Zoology. Later on, when Biotechnology course was introduced in the college during 1998-99, the department offered complementary Biochemistry to Biotechnology students also. The department also offers one Year PG Diploma Course in Diagnostic Molecular Science, which is approved by UGC under National Skill Qualification Framework (NSQF).
The pioneer of the department was Prof. A. Suresh Babu. He held important positions in various academic bodies of University of Kerala. His period of service was from Oct 1976-Mar 2007
Programmes offered
- Complementary Biochemistry for B.Sc.Botany and B.Sc.Zoology
- Complementary Biochemistry for B.Sc.Botany and Biotechnology
- One Year PG Diploma Course in Diagnostic Molecular Science
About the Course
Biochemistry is the study of biological phenomena at the molecular level. Its aim is to understand the fundamental chemical principles that govern complex biological systems. The major focuses include the basics in Biophysical Chemistry, Biomolecules, Enzymes and Bioenergetics, Intermediary Metabolism for Botany and Zoology graduates, while for biotechnology students the major thrust areas include Physical aspects of Biochemistry, Biomolecules, Physiology, Nutrition and Metabolism
The primary objectives of the course are 1) to give students a solid foundation in biological chemistry 2) to develop analytical and critical-thinking skills that allow independent exploration of biological phenomena through the scientific method 3) to introduce students to modern methods of biochemical experimentation within the disciplines of biochemistry and molecular biology.
Scope
As the biotechnology industry continues to grow and become an essential part of our socio-economic, scientific and industrial progress, jobs will be available through a variety of sectors, since biochemistry is an integral part of Biotechnology. Fields requiring skills in biochemistry include, but are not limited to, bio pharmaceutics, bioinformatics, toxicology, pharmacokinetics, functional genomics, environmental monitoring, industrial safety, DNA vaccines, bio-remediation, high throughput chemistry, and other related fields. Having good skills in any of these areas can put students in a position sought in various sectors.
Mission
Department is committed to create a genuine interest among students in studying and pursuing research in the field of Biochemistry.
Vision
To create a platform for Biochemistry research in Sree Narayana College especially in the field of drug development as the faculties have the expertise in this area.
Activities
We conduct seminar/workshop /orientation programs/extension activities on current relevant topics ensuring complete participation of our students.
Dr Vinod B.S
1 | Designation | Assistant Professor |
2 | Department | Biochemistry |
3 | Contact Numbers | 9447144677 |
4 | drvinodsnc@gmail.com | |
5 | Personal Web Page | https://www.researchgate.net/profile/Vinod_Balachandran |
6 | Date of Entry into Service | 05/01/2011 |
7 | Date of Retirement | 31/05/2035 |
8 | Edu. Qualifications | M.Sc., PhD, CSIR-JRF, ICMR-JRF, UGC-NET |
9 | Areas of Interest/Specialisation | Chemosensitization, Chemoresistance, Cell signalling |
10 | Courses/subject Taught | Biophysical chemistry
General Biochemistry Enzymes and bioenergetics Physiological aspects in Biochemistry Metabolism |
11 | Field of Research | Cancer Research |
12 | Guideship Details | N/A |
13 | Experience | 10 years |
14 | Memberships in Learned Bodies/Societies, If any | Life Member, Society of Biological Chemists
Life Member, Kerala Academy of Sciences Life member Association of Clinical Microbiologists & Biochemists |
15 | Scholarships/Fellowships Obtained |
Senior research fellowship from the Council of Scientific and Industrial Research, Govt. of India (September 2007- September 2010) Junior research fellowship from the Council of Scientific and Industrial Research, Govt. of India (September 2005- September 2007) Junior research fellowship from the Indian Council of Medical Research, Govt. of India on August 2004 UGC-NET by the University Grants Commission, Govt. of India on June 2005 |
16 | Extension Activities |
Organized various orientation programmes and recruitments as Co-ordinator of Career Guidance and Placement Cell
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17 | Papers Published |
1) Chitosan Encapsulation Enhances the Bioavailability and Tissue Retention of Curcumin and Improves its Efficacy in Preventing B[a]P-induced Lung Carcinogenesis. Vinod Vijayakurup, Arun Kumar T Thulasidasan, Mohan Shankar G, Archana.P Retnakumari, C Devika Nandan, Jannet Somaraj, Jayesh Antony, Vijai V Alex, Vinod Balachandran, Vijayasteltar Liju, Sankar Sundaram, Vinod Kumar G S, and Ruby Anto. Cancer Prevention Research 2019 Apr;12(4):225-236, IF- 4.021, ISSN: 1940-6207. 2) Heteronemin, a marine natural product, sensitizes acute myeloid leukemia cells towards cytarabine chemotherapy by regulating farnesylation of Ras. Minakshi Saikia, Archana P Retnakumari, Shabna Anwar, Nikhil P Anto, Rashmi Mittal, Shabna Shah, Kavya S Pillai, Balachandran S Vinod, Vidya Peter, Reeba Thomas and Ruby John Anto. Oncotarget. 2018; 9:18115-18127. IF- 5.168, ISSN: 1949-2553 3) Sensitized Luminescence from novel pyrazolone based β-diketonate complexes of Eu3+, D. B. Ambili Raj, S. V. Manoj, and B. S. Vinod, Bulletin of Pure & Applied Sciences- Section C, 2018,37: 64-69, ISSN 2320 320X 4) Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2–Akt axis. Balachandran S Vinod, H H Nair, V Vijayakurup, A Shabna, S Shah, A Krishna, K S Pillai, S Thankachan & R J Anto. Cell Death Discovery 1, (2015) doi:10.1038/cddiscovery.2015.61, ISSN 2058-7716 5) Phytochemicals as Chemosensitizers: From Molecular Mechanism to Clinical Significance. Balachandran S Vinod, T T Maliekal and R J Anto. Antioxid Redox Signal. 2013 Apr 10; 18(11):1307-48. doi: 10.1089/ars.2012.4573. IF- 7.407 6) Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil. Balachandran S Vinod, Jayesh Antony, Haritha H.Nair, Vineshkumar T Puliyappadamba, Minakshi Saikia, Sai Shyam Narayanan, Arathy Bevin and Ruby John Anto. Cell Death Dis. 2013 Feb 21; 4: e505. doi: 10.1038/cddis.2013.26. ISSN-2041-4889 IF- 5.99 7) Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its downregulation by curcumin is independent. Vineshkumar T P, Vino T Cheriyan, Smitha V Bava, Arun Kumar T Thulasidas, Balachandran S Vinod, Priya R Prabhu, Ranji Varghese, Arathy Bevin, Shalini Venugopal and Ruby John Anto. Mol Cancer. 2010 Aug 20; 9:220. doi: 10.1186/1476-4598-9-220.IF- 3.779 8) ATF2 maintains a subset of neural progenitors through CBF1/Notch independent Hes-1 expression and synergistically activates the expression of Hes-1 in Notch dependent neural progenitors. Rajendran Sanalkumar, Chandrasekharan Lalitha Indulekha, Thulasi Sheela Divya, Mundackal Sivaraman Divya, Ruby John Anto, Balachandran S Vinod, Sasidharan Vidyanand, Balusamy Jagatha, Shalini Venugopal, Jackson James,J Neurochem. 2010 May; 113(4):807-18. doi: 10.1111/j.1471-4159.2010.06574. IF-4.337 9) Curcumin sensitizes breast cancer cells to 5-FU through thymidylate synthase- dependent downregulation of NF-κB. Haritha H Nair, Balachandran S Vinod, Jayesh Antony, Minakshi Saikia, Ruby John Anto, Journal of Carcinogenesis 01/2012; Vol.11(Supplement 1): pp-S31 10) Human Epidermal Growth Factor Receptor signaling as a therapeutic target in breast cancer. Balachandran S Vinod and Ruby John Anto, Amala Research Bullettin 2006, 26, 18-27. Chapter in Text Books 1. Phenolics of the functional food – Curcumin- A nutraceutical with potential chemosensitive property.Role of dietary fibers and nutraceuticals in preventing diseases, Smitha V.B., Vinesh Kumar T.Puliyappadamba, Sreekanth C.N., Vinod B.S., Vino T. Cherian, Priya R Prabhu, Gayathri L.T, Ruby John anto. Edited by TA Augusti, 05/2009: pages 202-208; Pharma Med Press., ISBN: 9788188449725 Conference Proceedings 1) Pre-clinical validation of Thymidylate Synthase as the clinical target of curcumin in Chemosensitization of breast cancer towards 5-FU chemotherapy, Haritha H Nair, Aiswarya U S, Vijai V Alex, B S Vinod, Sankar S, Sadasivan C, Maria Zajac-Kaye, Ruby John Anto (2019) International Conference on Pharmacology Advances in Translational Sciences & Drug Discovery organized by Dept. of Pharmacology, National University of Singapore 2) Chemosensitization As A Strategy to Overcome Chemoresistance And Side Effects of Docetaxel; An Invitro Study: BS Vinod, Haritha H Nair, V Vinod, A Shabna, S Shabna & Ruby J Anto (2017) National seminar on recent trends in advanced chemistry research (RTACR-2017) organized by Dept. Of Chemistry on 25th and 26th may 2017 sponsored by DST (SERB) & KSCSTE at Sree Narayana College, Kollam. ISBN 978-93-5268-873-9 3) Evaluation Of The Chemosensitizing Efficacy Of Curcumin In 5-Fu Chemotherapy Against Breast Cancer: Swetha. M, Haritha H Nair, Liju V B, Aiswarya U.S, B.S Vinod and Ruby John Anto, at New Horizons in Cancer Treatment and Prevention: From Bench to Bedside organized by Department of Chemistry & Biochemistry, SN College, Kollam, sponsored by DST (SERB) & KSCSTE held from 16th to 17th March 2018 held at SN College, Kollam, ISBN 978-93-5300-765-2 4) Involvement of Mitogen activated protein kinases in the activation of AP-1 in 5-FU treated breast cancer cells, BS Vinod, D.B Ambiliraj, S.V.Manoj & Ruby J Anto (2018), Proceedings of the National Seminar on New Horizons in Cancer Treatment and Prevention: From Bench to Bedside (Pg. No:68-71) organized by Department of Chemistry & Biochemistry, SN College, Kollam, sponsored by DST (SERB) & KSCSTE held from 16th to 17th March 2018 held at SN College, Kollam, ISBN 978-93-5300-765-2
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18 | Papers Presented |
Invited talks 1.Title of the talk: Novel Strategies to Overcome Resistance to Chemotherapy in Cancer. Venue and event: SN College for Women, Kollam as part of the “PANLORE 2020” Seminar Series organized by Department of Biochemistry and Industrial Microbiology on 30.01.2020 2.Title of the talk: Webinar on “Digital awareness: Digilocker” organized by 3(K) Naval Unit NCC and IQAC, Sree Narayana College, Kollam on 18.07.2020 3.Title of the talk: “NPTEL Online Courses & Certification” organized by IQAC and NPTEL SNC Kollam Local Chapter on 14.08.2020 4. Title of the talk: “NPTEL E-Awareness Workshop for Students & Mentors” organized by IQAC and NPTEL SNC Kollam Local Chapter on 02.01.2021 ORAL PRESENTATIONS 1. B.S.Vinod and Ruby John Anto, Phytochemicals as chemosensitizers In vitro and In vivo Evidences at the One day Seminar on “Drug discovery from Natural Sources: “Recent Trends and Advances” organized by Department of Biochemistry as part of the Multidisciplinary Annual Seminar Series AGORA-2020 on 24/02/2020 2. BS Vinod, Haritha H Nair and Ruby John Anto, Regulatory role of Curcumin in overcoming chemoresistance to 5-FU in breast cancer cells via Cyclin D1 and Bcl2 at the International Seminar on Current Status and Challenges for Conservation and Sustainable Use of Biodiversity (ISCCSB 2020) from 22nd to 24th January, 2020 organized by the Department of Zoology, SN College, Kollam. 3. B.S Vinod , Haritha H.Nair, Sankar S, Sadasivan C, Maria Zajac Kaye & Ruby John Anto, Thymidylate Synthase As The Clinical Target For Curcumin-Mediated Chemosensitization Of Breast Cancer In 5-Fu Chemotherapy: In Vivo Evidences at the National Seminar On Current Trends and advances in Biological Sciences (CTAB-2020) from 5th to 7th February 2020, organized by the Department of Botany and Biotechnology, Bishop Moore College, Mavelikara 4. B.S.Vinod, Haritha H Nair and Ruby John Anto, Role of HER-2-Akt-mTOR signalling axis in regulating Resveratrol mediated Chemosensitization of Docetaxel at the National Seminar on Biomedical Research: Changing Paradigms Across Time from Jan 30th – Feb 1st 2019 organized by Dept.of Biochemistry, Govt.College, Kariavattom (Best Oral Presentation Award) 5. B.S.Vinod, Haritha H Nair, V Vinod, A Shabna, S Shabna and Ruby John Anto, Resveratrol mediated Chemosensitization of Docetaxel in HER2 overexpressing breast cancer cells, at the Albertian Knowledge Summit: An International Conference on Multidisciplinary research- organized by St.Albert’s College, Ernakulam on 11th January 2019. (Best Oral Presentation Award) 6. BS Vinod, Haritha H Nair and Ruby John Anto, Regulatory role of Curcumin in overcoming chemoresistance to 5-FU in breast cancer cells via Cyclin D1 and Bcl2, National Seminar on Reaching the Unreached through Science and Technology (RURTST-2018) organized by science departments of SN College, Kollam on 12th– 14th February 2018 sponsored by Department of environment and Climate Change & The Indian Science Congress, Cochin Chapter at Sree Narayana College, Kollam 7. B.S.Vinod, Haritha H Nair, V.Vinod, A Shabna, S.Shabna & RJ Anto, Chemosensitization as a strategy to overcome chemoresistance and side effects of docetaxel: An invitro study. National seminar on recent trends in advanced chemistry research (RTACR-2017) organized by Dept. Of Chemistry on 25th and 26th may 2017 sponsored by DST (SERB) & KSCSTE at Sree Narayana College, Kollam. 8. B.S.Vinod & Ruby John Anto, Molecular insights into the chemosensitizing efficacy of Curcumin in breast cancer cells at the National Symposium on Innovative Trends in Chemical Education and Research: Hurdles and Challenges (ITCER 2017) organized by department of chemistry, SN college, Kollam from 22nd march 2017 to 24th March 2017 sponsored by KSCSTE and BARC POSTERS PRESENTED 1. BS Vinod, Haritha H Nair, V Vinod , A Shabna, S Shabna and Ruby John Anto, Resveratrol-mediated down-regulation of HER-2-, Akt-,mTOR signaling axis plays a key role in chemosensitizing HER-2 over-expressing breast cancer cells to Docetaxel, at the 7th International Conference on Translational Cancer Research, sponsored by Society for Translational Cancer Research held at IIT Madras from 8th -11th February 2018 2. BS Vinod, Haritha H Nair, V Vinod , A Shabna, S.Shabna & Ruby John Anto, Resveratrol-mediated down-regulation of HER-2-Akt axis plays a pivotal role in chemosensitizing HER-2 over-expressing breast cancer cells to Docetaxel, 36th Annual Conference of Indian Association for Cancer Research on February 9-11, 2017 sponsored by Indian Association for Cancer Research at Amala Cancer Research Centre, Thrissur 3. Haritha H Nair, Balachandran S Vinod , Vinod V, Shabna A and Ruby John Anto, Resveratrol chemosensitizes HER-2-over-expressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2-Akt axis. The Global Cancer Summit, organized by the BioGenesis from 18-20 November 2015 at the J.N.Tata Auditorium, Indian Institute of Sciences Bengaluru, India. 4. Haritha H Nair, Balachandran S Vinod, Jayesh Antony, Minakshi Saikia and Ruby John Anto: Thymidylate synthase dependent NF-κB down-regulation plays pivotal role in efficacy of Curcumin in chemosensitizing breast cancer cells to 5-FU. 33rd annual convention of Indian Association for Cancer Research, at Kollam from February 13 to 15, 2014 (Best Poster Award) 5. Haritha H Nair, Balachandran S Vinod, Jayesh Antony, Minakshi Saikia, Ruby John Anto: Curcumin sensitizes breast cancer cells to 5-FU through thymidylate synthase- dependent downregulation of NF-κB: 3rd International Conference [Carcinogenesis 2012] on frontiers in carcinogenesis and preventive oncology: molecular mechanisms to therapeutics, New Delhi, India; 19-21November 2012 (Best Poster Award) 6. Balachandran S Vinod and Ruby John Anto, Resveratrol sensitizes breast cancer cells to apoptosis induced by Docetaxel, The International Cancer Research Symposium-2010: Defining and Translating Science behind the Disease’, December 20 -22, 2010, Thiruvananthapuram. 7. Balachandran S Vinod, Vinesh Kumar TP and Ruby John Anto: Curcumin sensitizes breast cancer cells to apoptosis induced by 5-fluorouracil:28th Annual Convention of IACR and International Symposium on Emerging Challenges for Approaches in Cancer Biology, February 21-24 2009, jointly organized by Indian Institute of Sciences and JNCASR, Bangalore |
19 | Books Published | 1. Proceedings of the National Seminar, New Horizons in Cancer Treatment and Prevention: From Bench to Bedside organized by Department of Chemistry & Biochemistry, SN College, Kollam, sponsored by DST (SERB) & KSCSTE held from 16th to 17th March 2018 held at SN College, Kollam, ISBN 978-93-5300-765-2 |
20 | Research Projects Undertaken | Evaluation of anticancer activity of Hemigraphis colorata, Student project awarded by KSCSTE (2019) |
21 | Orientation Courses Attended | 1. Attended the 140th Orientation Programme [IT-Oriented] conducted by UGC-HRDC, Trivandrum from 01-01-2015 to 28-01-2015 sponsored by UGC |
22 | Refresher Courses Attended |
1. Attended UGC-Sponsored Refresher Course in Environmental Sciences conducted by UGC-HRDC, Trivandrum from 02-02-2017 to 22-02-2017 2. Attended UGC-Sponsored Refresher Course in Life Sciences conducted by UGC-HRDC, Trivandrum from 11-07-2019 to 24-07-2019 |
23 | Seminars/Workshops/Trainings Organised |
1. World ozone day celebrations 2017 organized by the Department of Chemistry and Biochemistry sponsored by Kerala State Council for Science Technology and Environment (KSCSTE) on 20/09/2017 & 22/09/2017 at Sree Narayana College, Kollam 2. New Horizons in Cancer Treatment and Prevention: From Bench to Bedside organized by the Department of Chemistry and Biochemistry sponsored by DST (SERB) and Kerala State Council for Science Technology and Environment (KSCSTE) on 16/03/2018 to 17/03/2018 at Sree Narayana College, Kollam. 3. One day workshop on “Basic Bioinformatics Tools and Techniques” organized by Department of Biochemistry in collaboration with PTA Sree Narayana College, Kollam on 29/10/2019. 4. One day Seminar on “Drug discovery from Natural Sources: “Recent Trends and Advances” organized by Department of Biochemistry as part of the Multidisciplinary Annual Seminar Series AGORA-2020 on 24/02/2020 5. Awareness webinar on COVID19 entitled “Corona Virus Disease-2019: All You Need to Know’’ organized by Department of Biochemistry in association with IQAC, SN College, Kollam on 23/07/20. 6. Webinar on “Basics of Biomedical Nanotechnology” organized by Department of Biochemistry in association with IQAC on 10/10/2020 |
24 | Seminars/Conferences Attended |
1. International Webinar on “Recent Advances in Chemical Science” jointly organized by Postgraduate & Research Department of Chemistry and IQAC, Sree Narayana College, Kollam from 28th – 31st May 2020 2. One day seminar on wetlands, Climate Change and Future Security (World wetland day 2019) organized by Dept.of Zoology & Nature Club, SN College, Kollam on 8th February 2019 sponsored by KSCSTE 3. Two-day National Seminar on Recent Trends in Advanced Chemistry Research (RTACR-2017) organized by Dept. Of Chemistry on 25th and 26th may 2017 sponsored by DST (SERB) & KSCSTE at Sree Narayana College, Kollam. 4. World ozone day celebrations 2017 sponsored by Kerala State Council for Science Technology and Environment (KSCSTE) on 22nd September 2017 held at SN College, Kollam 5. Three Day National Seminar on Reaching the Unreached through Science and Technology (RURTST-2018) organized by Science departments of SN College, Kollam on 12/02/18 to 14/02/18 sponsored by Department of environment and Climate Change & The Indian Science Congress, Cochin Chapter at Sree Narayana College, Kollam 6. One day Seminar on Advanced Polymer Materials and Characterization organized by Dept. Of Chemistry on 13th March 2018 sponsored by Dr.K.Sundaresan Memorial Committe, Kollam. 7. 7th International Conference on Translational Cancer Research at IIT Madras from 8/02/18 to 11/02/18 sponsored by Society for Translational Cancer Research & IIT Madras 8. Three-day National Symposium on Innovative Trends in Chemical Education and Research: Hurdles and Challenges (ITCER 2017) organized by department of chemistry, SN college, Kollam from 22nd march 2017 to 24th March 2017 sponsored by KSCSTE and BARC 9. Two-day National Seminar on Ground water Augmentation: Problems, constraints organized by Department of Chemistry, Sree Narayana College, Kollam on June 29 and 30, 2016 |
25 | Workshops/Trainings Attended |
1. NPTEL E-Awareness workshop conducted by NPTEL, IIT Chennai along with Galgotias University, Uttar Pradesh on August 30, 2020 2. One Week online Short-term Faculty Development Programme on “ICT Tools for Teaching Learning Process- Post Pandemic Educational Strategies” which was delivered as MOOC with four quadrants, organised by Department of Physics and IQAC Sree Narayana College Kollam in collaboration with The Kerala State Higher Education Council from August 17-23, 2020 3. Short term course in “E-Teaching with Learning Management Systems”, 10-day online workshop Conducted by the All Kerala Private College Teachers Association in June 2020 4. 5 day online National Level Faculty Development programme on “Moodle-Learning Management System” from 19-05-2020 to 23-05-2020 organized by the Department of Computer Applications, MES College Marampally, in association with Spoken Tutorial, IIT Bombay. 5. One Week online Short-term Faculty Development Programme on “Implementation of Information and Communication Technology in Teaching” which was delivered as MOOC with four quadrants, organized by School of Legal Studies, Cochin University of Science and Technology in collaboration with The Kerala State Higher Education Council from July 18-24, 2020 6. Attended five day online hands-on workshop on Using Google Classroom: Effective Teaching Techniques from 27 April to 1 May 2020 conducted by the Internal Quality Assurance Cell (IQAC), St Gregorios College, Kottarakara, Kerala. 7. One day Workshop on Public Financial Management System (PFMS) on 21st August, 2019 organized by IQAC, SN College, Kollam. 8. Two-day international workshop on Human Chromosomes sponsored by Directorate of Collegiate Education, Govt. of Kerala on 9th -10th January 2018 at University college, Trivandrum 9. One day Workshop on Career advancement scheme for college teachers under UGC regulations on 17/04/2017 sponsored by IQAC, SNC Kollam 10. Two-day workshop on Research Methodology, Writing Practices, Language and soft skills from 27/03/2017 to 28/03/2017 organized by department of chemistry, SN College, Kollam sponsored by KSCSTE |
26 | Academic Responsibilities Undertaken |
1. Member, Board of Question setters Biochemistry, SB College, Changanacherry 2. Reviewer : Journal of Ayurveda and Integrative Medicine 3. Reviewer: Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 4. Reviewer: Plos One 5. Co-ordinator for the PG diploma course in Diagnostic Molecular Science, under UGC NSQF 6. Tutor: First semester B.Sc. Botany and Biotechnology |
27 | Duties Performed at College |
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28 | Awards/Honours/Patents | Best Oral presentation at the Albertian Knowledge Summit: An International Conference on Multidisciplinary research- organized by St.Albert’s College, Ernakulam (11.01.2019)
Best Oral presentation at the National Seminar on Biomedical Research: Changing Paradigms Across Time from Jan 30th – Feb 1st 2019 organized by Dept.of Biochemistry, Govt.College, Kariavattom |
29 | Collaboration/Consultancy | Research collaboration with Dr.Ruby John Anto, Scientist G, Rajiv Gandhi Centre for Biotechnology, Trivandrum
Academic collaboration with Sankar’s Health care and Diagnostics, Alappuzha |
Dr Ambili S
1 | Designation | Assistant Professor |
2 | Department | Biochemistry |
3 | Contact Numbers | 9497783709, 0471-2453123 |
4 | ambilisavithri@snckollam.ac.in, ambilisnc@gmail.com | |
5 | Personal Web Page | Nil |
6 | Date of Entry into Service | 10-01-2011 |
7 | Date of Retirement | 2027 |
8 | Edu. Qualifications | M Sc Biochemistry; Ph D Biochemistry; PGDCA |
9 | Areas of Interest/Specialisation | Drug development from higher plants, Pharmacology(in vivo studies)
Other areas of interest- Women Empowerment, IPR, Environment awareness programmes, Nutrition and food security, Tree gardening |
10 | Courses/subject Taught | UG
Biophysical chemistry, Biomolecules, Enzymes and Bioenergetics, Intermediary Metabolism Introduction to biochemistry,General Biochemistry, Physiological aspects in Biochemistry, Metabolism
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11 | Field of Research | Pharmacology |
12 | Guideship Details | Nil |
13 | Experience | Teaching Experience
Assistant Professor in Biochemistry, S N College, Kollam since 10th January 2011 and continuing.
Experience in S & T Management -5 years experience as Technical Officer in SRS (Science Research Scheme), the flagship programme of Kerala State Council for Science Technology and Environment, handling the technical aspects of project sanctioning. The projects are of basic research, applied and also of societal relevance.
Experience as Technical Officer in the Pharmacology Department, JNTBGRI, Palode, Thiruvananthapuram (5 yrs)
Women Scientists’ Cell, 6 months experience. Post Doctoral in Women Scientists’ Cell, Kerala State Council for Science Technology and Environment |
14 | Memberships in Learned Bodies/Societies, If any | Life Member of Indian Association of Biomedical Scientists (IABMS)
Life member of Kerala Academy of Sciences Life Member of ASCI Association |
15 | Scholarships/Fellowships Obtained | Post doctoral fellowship, Women Scientist Cell Kerala State Council for Science, Technology and Environment. Sasthra Bhavan , Pattom Thiruvananthapuram. 2010 |
16 | Extension Activities | Coordinator for the extension activity on “Solid waste management and development of homestead garden” Sree Narayana College, Kollam, 26th Oct, 2016.
Coordinator Healthy Diet Awareness Programme-Jan 2019 (2018-2019 academic year)
Coordinator Healthy Diet Awareness Programme Oct 2019 (2019-2020 academic year)
Coordinated the planting of 50 tree saplings in the campus of SN College, kollam in association with NSS unit with the help of State Medicinal plants board, and JNTBGRI 10-12-2019.
During the covid-19 pandemic lockdown period planted 31 fruit trees were planted in the neighborhood in view of increasing the nutritional as well as economic status of the state, May 2020
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17 | Papers Published | Papers Published
Ambili S, Subramoniam. A and Nagarajan. N.S. Studies on the Anti-hyperlipidemic Properties of Averrhoa bilimbi Linn. Fruit in Rats. Planta Medica 2009;75:55-58.
Ambili S, Anilkumar S and Subramoniam A. Hypolipidemic, antioxidant and cytotoxic properties of Benincasa hispida fruit juice. Biomedicine (2007); 27(2):72-76.
Ambili S and Subramoniam. A. Prevention and treatment of hyperlipidemia with neutraceuticals and herbal drugs in: Medicinal plants: Ethno-botanical Approach. Agrobios (India), Jodpur (2006) pg.(319-345). ISBN: 81-7754-253-2
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18 | Papers Presented |
Suma Somasekharan Ambili Savithri, , Reaction of resourcinol and acetophenone; green method. Presented in the National Symposium on The Innovative Trends in Chemical Education and Research: Hurdles and Successive Progress (ITCER-2017), March 22-24, 2017, Sree Narayana College, Kollam.
Ambili Savithri, Suma Somasekharan. Characterization of a few compounds from Averrhoa bilimbi Linn. Presented in the National seminar on Augmentation of ground water resources: problems, constraints and challenges.29th and 30th June 2016, Department of Chemistry, Sree Narayana College, Kollam.
Ambili Savithri, Suma Somasekharan. Studies on the antioxidant properties of Averrhoa bilimbi Linn fruits and isolation of compounds. Presented in the RBAT-II (2015) International Seminar on Recent Biochemical Approaches in Therapeutics Dec 9-11,2015. Department of Biochemistry, University of Kerala, Kariavattom 695581
Ambili S, Subramoniam A and Nagarajan NS. Averrhoa bilimbi Linn. fruits-A promising neutraceutical. Presented in the 3rd National Seminar on ‘Phytochemicals and Nutrition’ Feb 2009, Fatima Matha National College , Kollam, Kerala, India.
Ambili S, Subramoniam A and Nagarajan NS. Promising Anti-hyperlipidemic Properties of Averrhoa bilimbi Linn. Fruits in Rats. Presented in the 1st International Conference on Drug Design and Discovery held in Dubai, UAE, 4-7 Feb 2008. which hosted 15 Nobel Laureates.
Ambili. S, Anilkumar S and Subramoniam A. Hypolipidemic, antioxidant and cytotoxic properties of Benincasa hispida fruit juice. Presented in the Symposium on Bioresources in the Development of Medicine & 28th Annual Conference of Indian Association of Biomedical Scientists. Tiruchirapalli., Tamilnadu , India,2007.
Ambili S, Subramoniam A and Nagarajan NS. Studies on the Antihyperlipidemic property of Averrhoa bilimbi Linn(Fruit) in High Fat Diet Fed Rats. Presented in the National Seminar on Recent Trends in Isolation, Characterization, Synthesis and Biological Studies of Organic Compounds” 5th and 6th March 2004. GRU, Tamil Nadu, India
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19 | Books Published | Nil |
20 | Research Projects Undertaken | (as Co-investigator) Tropical Botanic Garden & Research Institute Funded Projects: ( 1 & 2 )
(1)Pharmacological evaluation of Hemidesmus indicus root (extract/active fraction) for its utility as a phytomedicine to improve efficacy of ORS. (2) Studies on the mechanism of action and pharmacological profile of the active fraction of Trichopus zeylanicus leaf towards developing the same as a standardized anti-stress/adaptogenic herbal drug (phytomedicine). 3) Minor-UGC funded- Studies on the antioxidant properties of Averrhoa bilimbi Linn fruits MRP(S)-246/12-12/KLKE006/UGC-SWRO, Dated 29/3/13
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21 | Orientation Courses Attended | UGC –Sponsored Orientation Programme conducted by UGC-Academic staff College, University of Kerala, Kariavattom from 01-01-2013 to 28-01-2013
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22 | Refresher Courses Attended | Refresher Course in Life Sciences by Academic Staff
College, University of Kerala, Kariavattom , Thiruvananthapuram from 02-07-2014 to 22-7-2014
Refresher Programme in Environmental Studies, UGC-HRDC, Kerala University during 11-01-2020 to 24-01-2020
Short term course in Gender Sensitization at UGC-HRDC, University of Kerala, during 22-11-2019-28-11-2019.
Short term course in climate change at UGC-HRDC, Kannur University during 13-12-2019 to 19-12-2019.
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23 | Seminars/Workshops/Trainings Organised | Convenor of the Wetland Day Celebration February 01-03, 2017 funded by Kerala State Council for Science, Technology and Environment (KSCSTE), Thiruvananthapuram.
As Coordinator, Quiz Club organized an Intercollegiate Quiz Contest ‘Maieutic – 2018’ on General Awareness Sree Narayana College. Kollam on 12th March 2018 at S N College, Kollam, funded by PTA As Coordinator, Quiz Club, Sree Narayana College, Kollam, organized quiz competition “INQUISITIVE 2018” on 08 th November 2018 at, Sree Narayana College, Kollam ,funded by PTA. Organised departmental seminar series AGORA-2019. One day seminar on “Life style and Chronic Diseases” on 13/02/2019 at SN College, Kollam. Funded by PTA
As quiz club coordinator, conducted Interdepartmental Quiz Contest on General Awareness ‘INSIGHTS 2K19’ at Sree Narayana College, Kollam. 06-12-2019 funded by PTA
Coordinated the Webinar entitled “Role of phytochemicals in COVID-19 management” on 29-07-2020.
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24 | Seminars/Conferences Attended | National seminar on “Biomedical Research :Changing Paradigms across time held during Jan 30th to Feb 1st , 2019 at Department of Biochemistry, Government College, Kariavattom, Thiruvananthapuram.
31st Kerala Science Congress held during 2nd and 3rd Feb 2019 at Fatima Mata National College, Kollam
Seminar on Wetlands, Climate Change and Future Security (World Wetland day 2019) organized by Department of Zoology & Nature Club , SN College, Kollam on 8th Feb 2019.
International symposium on “Metabolism and aging” organized by Mar Ivanious College(Autonomous ) Thiruvananthapuram on 16-17 July 2019.
National Seminar, Sree Narayana College, Kollam Reaching the unreached through science and technology RURTST-2018, 12-14 Feb 2018, funded by The Indian Science Congress Association Cochin Chapter and Department of Environment & Climate Change.
New Horizons in Cancer Treatment and Prevention: From Bench to Bedside National Seminar,Biochemistry Department, Sree Narayana College, Kollam,16th and 17th Mar 2018 funded by DST (SERB) and KSCSTE.
National Symposium on The Innovative Trends in Chemical Education and Research: Hurdles and Successive Progress (ITCER-2017) Department of Chemistry, Sree Narayana College, Kollam March 22-24, 2017.
Seminar on Augmentation of ground water resources: problems, constraints and challenges. Department of Chemistry, Sree Narayana College, Kollam29th and 30th June 2016
National seminar on Cancer Biology: New Frontiers and Avenues, Department of Biochemistry, University College, Thiruvananthapuram on 16-12-2016 sponsored by Directorate of Collegiate Education.
International seminar on Recent Biochemical Approaches in Therapeutics (RBAT-II) Dec 9-11, 2015 conducted by Department of Biochemistry, University of Kerala, Kariavattom.
International Symposium on Phytochemistry & Dr A Hisham Endowment Award Ceremony organized by Kerala Academy of Sciences (KAS) on 25th April 2015, at Kerala State Science and Technology Museum, Thiruvananthapuram.
Participated in the national seminar “ Physical and Bio-medical Applications in Nano Technology” held during October 12-14, 2011 at S N College, Kollam.
International Seminar on Recent Developments in Stem Cell Research. Payyanoor, 2009, Kerala
Participated in the Brain Storming Session of the Women Scientist’s Cell, KSCSTE on 27th July 2009 at Sasthra Bhavan, Thiruvananthapuram
XXVII Annual Conference of Indian Association of Biomedical Scientists and National Symposium on Current Trends in the Development of Herbal Drugs held at Thiruvananthapuram, Nov 2006.
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25 | Workshops/Trainings Attended |
Participated in the two day workshop on “Microscale Experiments in Chemistry” organized by the Board of Studies in Chemistry (Pass) University of Kerala and Academy of Chemistry Teachers (ACT) on March 13th and 14th 2014 at S N College, Kollam.
International two day Worshop- at University College, Thiruvananthapuram on Human Chromosomes, 9th and 10th January 2018 funded by Directorate of collegiate education.
Research Methodology, Writing Practices, Language and soft skills 27/3/2017 and 28/3/2017 funded by KSCSTE
Participated in the Workshop on the recommendations of Prof. B. Hrdayakumari Committee Report organized by Board of Studies in Biochemistry held on 25th March 2014 at Department of Biochemistry, University of Kerala, Kariavattom.
DST training programme on “Ethnic issues and community resources management” for young women scientists – at Indian Institute of Forest Management, Bhopal, India during 18th -22nd Jan 2010.
DST training programme on “Leadership and Team Building” for women scientists at Administrative Staff College of India, Bella Vista, Hyderabad, India during 26th-30th July 2010.
Training in Intellectual Property Right (IPR) conducted in the Institute of Management in Government, Kerala, India from 28 to 30 July 2008.
Participated in the one day workshop on “50 years of DNA- the blue print of life and 25 years of IVF” at the Institute of Engineers, Thiruvananthapuram, on 2003.
National Workshop on Indigenous knowledge organized by TBGRI at Kanakakunnu Palace, Thiruvananthapuram, 2002.
Workshop on Biodiversity Conservation, 18 to 23, Feb 1993 at TBGRI.
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26 | Academic Responsibilities Undertaken |
Member of Board of Studies of Biochemistry(2012-2015)).University of Kerala
Involved in the revision of syllabus of Botany & Biotechnology (CBCSS restructured)
In the revision of syllabus Biochemistry (Core) and Industrial Microbiology for the implementation of Environmental Studies as a core course.
Guiding post graduate projects
As additional examiner for university practical examinations from 2012 to continuing.
As additional examiner for paper valuation of university examinations from 2011 to continuing.
As invigilator for the various university examinations from 2011 to continuing. |
27 | Duties Performed at College | Theory and practical classes for Botany, Zoology and Biotechnology (U G complementary).
Coordinating club activities and to undertake duties in various committees
Invigilation for the university examinations
University and internal paper valuation
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28 | Awards/Honours/Patents | Received travel award from INSA for presenting paper in the 1st International Conference on Drug Design and Discovery held in Dubai, UAE-2008
Received travel award from Centre for Cooperation in Science and Technology among Developing Societies (CCSTDS ) for presenting paper in the 1st International Conference on Drug Design and Discovery held in Dubai, UAE-2008
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29 | Collaboration/Consultancy | Collaboration with Indian Institute of Science, Bangalore |
30 | Passport size photo |
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Peer reviewed Journals
- Chitosan Encapsulation Enhances the Bioavailability and Tissue Retention of Curcumin and Improves its Efficacy in Preventing B[a]P-induced Lung Carcinogenesis. Vinod Vijayakurup, Arun Kumar T Thulasidasan, Mohan Shankar G, Archana.P Retnakumari, C Devika Nandan, Jannet Somaraj, Jayesh Antony, Vijai V Alex, Vinod Balachandran, Vijayasteltar Liju, Sankar Sundaram, Vinod Kumar G S, and Ruby Anto. Cancer Prevention Research 2019 Apr;12(4):225-236, IF- 4.021, ISSN: 1940-6207.
- Heteronemin, a marine natural product, sensitizes acute myeloid leukemia cells towards cytarabine chemotherapy by regulating farnesylation of Ras. Minakshi Saikia, Archana P Retnakumari, Shabna Anwar, Nikhil P Anto, Rashmi Mittal, Shabna Shah, Kavya S Pillai, Balachandran S Vinod, Vidya Peter, Reeba Thomas and Ruby John Anto. Oncotarget. 2018; 9:18115-18127. IF- 5.168, ISSN: 1949-2553
- Sensitized Luminescence from novel pyrazolone based β-diketonate complexes of Eu3+, D. B. Ambili Raj, S. V. Manoj, and B.S. Vinod, Bulletin of Pure & Applied Sciences- Section C, 2018,37: 64-69, ISSN 2320 320X
- Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2–Akt axis. Balachandran S Vinod, H H Nair, V Vijayakurup, A Shabna, S Shah, A Krishna, K S Pillai, S Thankachan & R J Anto. Cell Death Discovery 1, (2015) doi:10.1038/cddiscovery.2015.61, ISSN 2058-7716
- Phytochemicals as Chemosensitizers: From Molecular Mechanism to Clinical Significance. Balachandran S Vinod, T T Maliekal and R J Anto. Antioxid Redox Signal. 2013 Apr 10; 18(11):1307-48. doi: 10.1089/ars.2012.4573. IF- 7.407
- Mechanistic evaluation of the signaling events regulating curcumin-mediatedchemosensitization of breast cancer cells to 5-fluorouracil. Balachandran S Vinod, Jayesh Antony, Haritha H.Nair, Vineshkumar T Puliyappadamba, Minakshi Saikia, Sai Shyam Narayanan, Arathy Bevin and Ruby John Anto. Cell Death Dis. 2013 Feb 21; 4: e505. doi: 10.1038/cddis.2013.26.ISSN-2041-4889 IF- 5.99
- Curcumin sensitizes breast cancer cells to 5-FU through thymidylate synthase- dependent downregulation of NF-κB. Haritha H Nair, Balachandran S Vinod, Jayesh Antony, Minakshi Saikia, Ruby John Anto, Journal of Carcinogenesis 01/2012; Vol.11(Supplement 1): pp-S31
- Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its downregulation by curcumin is independent. Vineshkumar T P, Vino T Cheriyan, Smitha V Bava, Arun Kumar T Thulasidas, Balachandran S Vinod, Priya R Prabhu, Ranji Varghese, Arathy Bevin, Shalini Venugopal and Ruby John Anto. Mol Cancer. 2010 Aug 20; 9:220. doi: 10.1186/1476-4598-9-220.IF- 3.779
- ATF2 maintains a subset of neural progenitors through CBF1/Notch independent Hes-1 expression and synergistically activates the expression of Hes-1 in Notch dependent neural progenitors. Rajendran Sanalkumar, Chandrasekharan Lalitha Indulekha, Thulasi Sheela Divya, Mundackal Sivaraman Divya, Ruby John Anto, Balachandran S Vinod, SasidharanVidyanand, Balusamy Jagatha, Shalini Venugopal, Jackson James, J Neurochem. 2010 May; 113(4):807-18. IF-4.337
- Studies on the anti-hyperlipidemic Properties of Averrhoa bilimbi fruit in rats. Ambili S, A and Nagarajan. N.S. Planta Med. 2009; 75: 55-58.
- Hypolipidemic, antioxidant and cytotoxic properties of Benincasa hispida fruit juice. Ambili S, Anilkumar S and Subramoniam A. Biomedicine 2007;27(2):72-76.
- Human Epidermal Growth Factor Receptor signaling as a therapeutic target in breast cancer. Balachandran S Vinod and Ruby John Anto, Amala Research Bulletin 2006, 26, 18-27.
- Prevention and treatment of hyperlipidemia with neutraceuticals and herbal drugs in: Medicinal plants: Ethno-botanical Approach. Ambili S and Subramoniam. A. Agrobios (India), Jodpur (2006) pg.(319-345). ISBN: 81-7754-253-2
Conference proceedings
- Involvement of Mitogen activated protein kinases in the activation of AP-1 in 5-FU treated breast cancer cells. BS Vinod, DB Ambiliraj, SV.Manoj & Ruby J Anto (2018), Proceedings of the National Seminar on New Horizons in Cancer Treatment and Prevention: From Bench to Bedside (Pg. No:68-71) organized by Department of Chemistry & Biochemistry, SN College, Kollam, sponsored by DST (SERB) & KSCSTE held from 16th to 17th March 2018 held at SN College, Kollam, ISBN 978-93-5300-765-2
- Evaluation of the Chemosensitizing efficacy of Curcumin in 5-Fu chemotherapy against breast cancer. Swetha. M, Haritha H Nair, Liju V B, Aiswarya U.S, S Vinod and Ruby John Anto, Proceedings of the National Seminar on New Horizons in Cancer Treatment and Prevention: From Bench to Bedside organized by Department of Chemistry & Biochemistry, SN College, Kollam, sponsored by DST (SERB) & KSCSTE held from 16th to 17th March 2018 held at SN College, Kollam, ISBN 978-93-5300-765-2
- Chemosensitization as a strategy to overcome chemoresistance and side effects of Docetaxel; an Invitro study. BS Vinod, Haritha H Nair, V Vinod, A Shabna, S Shabna & Ruby J Anto (2017) National seminar on recent trends in advanced chemistry research (RTACR-2017) organized by Dept. Of Chemistry on 25th and 26th may 2017 sponsored by DST (SERB) & KSCSTE at Sree Narayana College, Kollam. ISBN 978-93-5268-873-9
- HER-2-Akt signaling axis regulates the efficacy of resveratrol in chemosensitizing HER-2-over-expressing breast cancer cells to docetaxel. Haritha H Nair, BS Vinod, V Vinod, Aiswarya U.S, Vijai V.Alex, Nesteena K.N, Ruby John Anto, at International Conference on Nutraceuticals and Chronic Diseases sponsored by Society for Nutraceuticals and Chronic diseases & IIT, Guwahati, Assam on September 1st – 3rd 2017
Research
- Pharmacological evaluation of Hemidesmus indicus root (extract/active fraction) for its utility as a phytomedicine to improve efficacy of ORS.
- Studies on the mechanism of action and pharmacological profile of the active fraction of Trichopus zeylanicus leaf towards developing the same as a standardized anti-stress/adaptogenic herbal drug (phytomedicine).
- Minor-UGC funded- Studies on the antioxidant properties of Averrhoa bilimbi Linn fruits MRP(S)-246/12-12/KLKE006/UGC-SWRO, Dated 29/3/13
- Evaluation of anticancer activity of Hemigraphis colorata, KSCSTE, Student project (2018-2019)
- Antimicrobial and anticancer activity of Ceratopteris thalictroids (L) brouguiart (2018-2019)
- Studies on the chemical components and antioxidant properties of Ceratopteris thalictroids (L) brouguiart KSCSTE, Student project (2017-2018)
Vinod Balachandran – Google Scholar
Scopus preview – Balachandran, Vinod – Author details – Scopus
- NPTEL E-Awareness Workshop for Students & Mentors in association with IQAC and NPTEL SNC Kollam Local Chapter on 02/01/2021
- Webinar on “Basics of Biomedical Nanotechnology” in association with IQAC on 10/10/2020
- NPTEL Online Courses & Certification in association with IQAC and NPTEL SNC Kollam Local Chapter on 14/08/2020
- Webinar on “Role of phytochemicals in COVID-19 management” in association with IQAC, SN College, Kollam on 29/07/2020.
- Awareness webinar on COVID19 entitled “Corona Virus Disease-2019: All You Need to Know’’ in association with IQAC, SN College, Kollam on 23/07/20.
- One day Seminar on “Drug discovery from Natural Sources: “Recent Trends and Advances” organized as part of the Multidisciplinary Annual Seminar Series AGORA-2020 on 24/02/2020
- Planting of 50 tree saplings in the campus of SN College, Kollam in association with NSS unit with the help of State Medicinal plants board on 10/12/2019
- Interdepartmental Quiz Contest on General Awareness ‘INSIGHTS 2K19’ at Sree Narayana College, Kollam. 06/12/2019 funded by PTA
- One day workshop on “Basic Bioinformatics Tools and Techniques” in collaboration with PTA Sree Narayana College, Kollam on 29/10/2019
- One day seminar on “Life style and Chronic Diseases” on 13/02/2019 at SN College, Kollam. Funded by PTA
- Quiz competition “INQUISITIVE 2018” on 08/11/2018 at, Sree Narayana College, Kollam, funded by PTA.
- New Horizons in Cancer Treatment and Prevention: From Bench to Bedside sponsored by DST (SERB) and Kerala State Council for Science Technology and Environment (KSCSTE) on 16/03/2018 to 17/03/2018 at Sree Narayana College, Kollam.
- Intercollegiate Quiz Contest ‘Maieutic – 2018’ on General Awareness 12/03/2018 at S N College, Kollam, funded by PTA
- World ozone day celebrations 2017 sponsored by Kerala State Council for Science Technology and Environment (KSCSTE) on 20/09/2017 & 22/09/2017 at Sree Narayana College, Kollam.
- Wetland Day Celebration February 01-03, 2017 funded by Kerala State Council for Science, Technology and Environment (KSCSTE), Thiruvananthapuram.
- “Solid waste management and development of homestead garden” Sree Narayana College, Kollam, 26/10/2016.